cTnI

Quantitative determination of cTnI in human plasma Cardiac troponin I (cTnI) is a contractile protein exclusively present in the cardiac muscle. It is one of three subunits of the troponin complex (I, T, C), which with tropomyosin are bound to actinin the thin filament of the myofibril. Its physiological role is to inhibit the ATPase activity of the Its physiological role is to inhibit the ATPase activity of the actin-myosincomplex in the absence of calcium, and therefore, to prevent muscular contraction.

NT-proBNP

Quantitative determinationof NT-proBNP (N-terminal pro B-type natriuretic peptide) in human serum and plasma. Clinical informationand imaging procedures are used to diagnose left ventricular dysfunction. The significance of natriuretic peptides in the control of cardiovascular system function has been demonstrated. Initial studiesreveal that natriuretic peptides can be used for diagnostic clinical problems associated with left ventricular dysfunction. Thefollowing natriuretic peptides have been described: atrial natriuretic peptide (ANP), B-typenatriuretic peptide (BNP), and C-typenatriuretic peptide (CNP).

CK-MB

Quantitative de-termination of Creatine Kinase-MB(CK-MB) concentrationin human serum and plasma. CK-MB is acardiac marker used to assist diagnoses of an acutemyocardial infarction.It is one of the three tissue isoforms (with CK-BB and CK-MM) of creatine kinase (CK). CK-MB is made up of twosub-units (MW= 40,000 each): M sub-unit, expressed in muscle, and B sub-unit, expressed inbrain. CK-MM and CK-MB are distributed primarily in the skeletalmuscle and heart muscle, respectively, while CK-BB is pre-sent mainly in the brain and in tissues composed of smooth muscle. Following myocardial infarction the CK-MBlevel rises and reaches a peak between 18-24hrs, the increase being similar to that of the total CK activity.

MYO

Quantitative determination of Myoglobin (MYO) concentration in human serum and plasma Myoglobin is a tightly folded, globular heme-protein located in the cytoplasm of both skeletal and cardiac muscle cells. And it is an iron-and oxygen-binding protein found in the muscle tissue of vertebrates in general and in almost all mammals. It is related to hemoglobin, which is the iron-and oxygen-binding protein in blood, specifically in thered blood cells. In humans, myoglobin is only found in the bloodstream after muscle injury.

D-Dimer

Quantitative determination of D-Dimer in human plasma D-Dimer is a degradation product of crosslinked fibrin and the elevated concentration of D-Dimer indicates increased coagulation and fibrinolytic activities. D-dimer testing is of clinical use when there is a suspicion of deep venous thrombosis (DVT) or pulmonary embolism (PE). Coagulation disorders are relatively frequently encountered among COVID-19 patients, especially among those with severe disease.